Bob Nickas has organized more than ninety exhibitions since 1984, and earned a reputation for an individual style that transgresses the accepted. Nickas was Curatorial Advisor at P.S.1/MoMA in New York between 2004-07, where his exhibitions includeLee Lozano: Drawn From Life; William Gedney—Christopher Wool: Into the Night; Stephen Shore: American Surfaces; and Wolfgang Tillmans: Freedom From The Known. He served on the team for the 2003 Biennale de Lyon, contributed a section to Aperto at the 1993 Venice Biennale, and collaborated with Cady Noland on her installation for Documenta IX in 1992.

His books include Painting Abstraction: New Elements In Abstract Painting, Theft Is Vision, Live Free or Die: Collected Writings 1985-1999, and The Dept. of Corrections. He is one of the authors of Defining Contemporary Art: 25 Years In 200 Pivotal Artworks, and of No Problem: Cologne/New York 1984-1989. 30/130, a survey of his books, catalogs and zines—130 produced over the past 30 years—as well as records, editions and ephemera, was presented at White Columns in 2015.